M. Pharm II Semester Supplementary Examinations, February 2016
NOVEL DRUG DELIVERY SYSTEMS – I
(For students admitted in 2009, 2010 & 2011 only)
(Pharmaceutics)
Max Marks: 60 Time: 3 hours
Answer any FIVE questions
All questions carry equal marks
1. (a) What are controlled release drug delivery system? Discuss about various factors influencing the design of controlled release system.
(b) Classify various types of bio compatible polymers. Give examples.
2. Discuss the principles and formulation of controlled release system based on diffusion and reservoir devices.
3. What are gastroretentive drug delivery system? Give examples. Discuss the formulation on development of any two such systems.
4. (a) Enlist various types of transmucosal drug delivery system. Discuss the challenges in the development of ocular drug delivery system.
(b) Discuss the limitations of Nasal drug delivery system.
5. (a) Discuss in brief the development of matrix type of transdermal drug delivery system. What are permentation enhancers. Give their mechanisms with examples.
(b) write the principles of iontophoresis and micro-needle based system.
6. (a) Discuss various approaches in the design of colon specific drug delivery system.
(b) Explain various evaluation methods of colon specific systems.
7. (a) what various types and purposes of prodrug for controlled release of drugs.
(b) Discuss about site specific prodrug approaches with examples.
8. Write the salient features of the following
(a) Medicated chewing gums.
(b) Osmotic pressure controlled systems.
(c) Medicated waters.
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