Novel Drug Delivery Systems -I , M.Pharm Previous Paper – Nov 2012

1 Explain in detail about the following terms:
(a) Delayed release.
(b) Controlled release.
(c) Prolonged release.
(d) Sustained release

2 (a) Differentiate dissolution and diffusion controlled drug delivery system.

(b) write a note pH independent oral controlled release system.

3 (a) Explain the types of ion exchange resins used in oral controlled system

(b) Discuss in detailed about GADDS.

4 (a) Enumerate various approaches involved in the delivery of drug in to the eye.

(b) write a note on vaginal drug delivery system.

5 (a) Describe the classification of transdermal devices with neat diagram.

(b) Briefly explain iontophoretic drug delivery system.

6 (a) Explain advantages of colon targeted drug delivery system over conventional drug delivery. Enumerate the criteria for selection of drugs for such system.

(b) Describe various approaches used for site specific drug delivery to colon.

7 Write a note on:
(a) Pharmacosomes.

(b) Drug targeting through antibodies.

8. (a) what are pressures controlled drug delivery systems? Explain hydrodynamic pressure controlled drug delivery systems.

(b) write a note on medicated chewing gums.